genetic testing through Genesight

A close-up, computer-generated image of a DNA double helix structure with colorful molecular particles surrounding and along it, set against a gradient background.

  • GeneSight® Pharmacogenomic Testing (Genetic Medication Testing)

    We offer GeneSight® genetic testing (pharmacogenomic testing / psychotropic medication testing) to help guide psychiatric medication selection and medication management.

    GeneSight testing evaluates how your genes may affect:

    • Medication metabolism

    • Drug-gene interactions

    • Response to antidepressants, anti-anxiety medications, ADHD medications, and mood stabilizers

    • Medication side effect risk and tolerability

    GeneSight does not identify a single “best medication,” but provides clinically relevant genetic information to support precision psychiatry and individualized treatment planning for mental health conditions including depression, anxiety, ADHD, bipolar disorder, autism-related treatment considerations, OCD, and PTSD.

    At-Home Testing Process

    GeneSight testing is completed at home. A testing kit is shipped directly to the patient via FedEx. The patient completes a simple, non-invasive cheek swab and returns the kit using prepaid FedEx shipping materials. Results are typically available within a few days and are reviewed with your provider as part of a personalized treatment plan.

    MTHFR Gene Variants & Methylation Support

    Genetic testing may also provide insight into MTHFR gene variants and methylation pathways, which may influence:

    • Neurotransmitter production and regulation

    • Folate and vitamin B12 metabolism

    • Energy, mood regulation, and cognitive functioning

    • Response to psychiatric medications and supplementation needs

    In some cases, this information may help guide discussion around methylated vs. standard B12 supplementation and broader metabolic and nutritional support as part of an individualized treatment plan.

    At ACAP, we use precision psychiatry (personalized mental health care) to move beyond trial-and-error prescribing by combining:

    • Psychiatric evaluation and diagnosis

    • Medication history and prior treatment response

    • Genetic testing (GeneSight pharmacogenomic testing)

    • MTHFR and methylation-related considerations

    • Individual symptoms, developmental history, and treatment goals

    This approach supports more informed, individualized care for depression, anxiety disorders, ADHD, bipolar disorder, autism spectrum disorder, OCD, PTSD, and related psychiatric conditions.

    Who May Benefit from Genetic & Lab Testing

    Genetic and lab testing may be helpful for individuals who:

    • Have experienced side effects from psychiatric medications

    • Have not responded well to multiple medication trials

    • Are starting psychiatric medication and want additional genetic guidance

    • Have a family history of medication sensitivity or treatment resistance

    • Have complex conditions such as ADHD, autism, bipolar disorder, or treatment-resistant depression

    • Want a more personalized, precision psychiatry approach to mental health care

    Insurance & Cost Information

    Medicare and Medicaid patients typically have $0 out-of-pocket cost for GeneSight testing. For commercially insured patients, over 98% pay $330 or less, depending on insurance coverage.

    Genetic Testing for Personalized Mental Health Care

    At Adolescent Child & Adult Psychiatry (ACAP), our goal is to provide evidence-based, personalized psychiatric care using a combination of clinical expertise and advanced genetic testing. GeneSight testing, MTHFR considerations, and methylation-related insights allow us to better understand medication response and support individualized treatment planning.

    If you are interested in GeneSight testing, pharmacogenomic testing, in Raleigh, North Carolina, contact Adolescent Child & Adult Psychiatry (ACAP) to learn more.